Sunday, June 3, 2012

Kenny Florian officially retires from MMA

Kenny Florian officially announced his retirement from fighting on Thursday. He had been contemplating walking away from the Octagon after a back injury. He walks away as one of the fighters who helped the UFC build to its current size.

Though Florian had three title shots and didn't win any, his career had plenty of highlights:

Cutting down to featherweight and beating Diego Nunes at UFC 131: After starting in the UFC at 185 lbs. and methodically working down to 155 lbs., the already thin Florian wanted a shot at featherweight and champion Jose Aldo. To get that shot, he first had to get through Diego Nunes, both to prove that he could cut down to 145 and that he could win at that weight. He did it, beating Nunes in a unanimous decision.

"I want BJ's belt!": Florian had one title shot against Sean Sherk. It was early in his UFC career, and he wasn't quite ready. With six straight lightweight wins, Florian had the credentials but it couldn't hurt to ask for it. After submitting Joe Stevenson in the first round, Florian said the phrase that was used in ubiquitous commercials: "I want BJ's belt!"

Stopping the Roger Huerta train at UFC 87: Heading into this fight, Huerta had a ton of hype surrounding him. He hadn't lost in the UFC and his most recent fight was a thrilling, comeback win over Clay Guida. If he won, he was expected to get a title shot. Florian wouldn't let that happen. He dominated Huerta for three rounds on the way to a unanimous decision.

TKO of Alex Karalexis at Ultimate Fight Night 1: After fighting at middleweight for "The Ultimate Fighter" and getting to the finals, Florian cut down to welterweight. Those Florian "Hellbows" helped him make a post-TUF mark. He made a huge cut across Karalexis' nose and won by TKO in the second round.

Now, the smart and articulate Florian will have more time to lend his voice and insight to the UFC's broadcasts on Fuel TV.

What was your favorite KenFlo moment? Tell us in the comments, on Facebook or on Twitter.

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Saturday, June 2, 2012

Hip-Hopping, Foot-Stomping Lineup for National Aboriginal Day as ...

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FALLING SHEEP! | Weekly World News

Sheep have been falling from the sky over Melbourne, Australia!

Falling sheep hit vehicles all across the Australian city of Melbourne. ?Some thought they came from a truck carrying livestock, but authorities later confirmed ? they just fell from the sky!

One truck carrying 400 sheep hung precariously on a bridge and its cargo plunged on to the road below. ?This confused authorities, because at the same time sheep were falling on buildings, homes and in swimming pools.

Hundreds of cars were smashed as they were hit by the falling sheep and many ?swerved to avoid them.

Many sheep were killed or injured, but Melbourne police said there were no human casualties. ?Though some humans were arrested for trying to drag away some dead ship.

So, what caused the sheep to fall from the sky? ??We have no idea, but there are many in the department that think aliens stole the sheep last week, brought them into their spaceships and then just started pummeling our citizens.?

WWN can confirm that over 5,000 sheep mysteriously disappeared in and around Melbourne over the last six weeks. ?And now? the sheep are being used as missiles.

?It?s definitely Gootans,? said Dr. Susan Begley of the U.N. Panel of Extraterrestrials. ?Gootans have been known to attack with sheep.?

Bottom line ? keep your heads up, and watch out for falling sheep!

Here?s the original ? though inaccurate ? report of the falling sheep.

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Alexander Kinyua, Maryland College Student, Admits Devouring Roommate's Brain and Heart


Maybe this zombie apocalypse thing really does have legs.

In another horrifying incident of human flesh-eating, Alexander Kinyua, a student in Maryland, allegedly admitted to devouring his roommate's brain and heart.

The 21-year-old Morgan State University student says he killed Kujoe Bonsafo Agyei-Kodie, who was reported missing last Friday, cops told the Baltimore Sun.

Kinyua's father called police late Tuesday night when Kinyua's brother reportedly found human remains, a head and two hands, in a metal tin in the basement.

Alexander Kinyua Mug ShotKujoe Bonsafo Agyei-Kodie Photo

The brother and father left the room for a short time, but when they came back, the body parts had been moved and Alexander Kinyua was washing out the tin.

Officers searched the house and arrested Kinyua.

The man then allegedly confessed a shocking revelation eerily reminiscent of Rudy Eugene: not only had he killed Agyei-Kodie by cutting him up with a knife and then dismembered him, he ingested parts of the victim's brain and all of his heart.

He allegedly dropped most of the remains in a dumpster.

It's yet unclear what Kinyua's motive may have been (no, there were no bath salts involved), but he was charged with first-degree murder on Wednesday.

The gruesome case comes on the heels of a similar attack in Miami, in which Rudy Eugene was killed after eating homeless man Ronald Poppo's face.

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Friday, June 1, 2012

Warren says she told schools of Native heritage (The Arizona Republic)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

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University of Tennessee professor uncovers clues about asteroid that will pass near Earth

University of Tennessee professor uncovers clues about asteroid that will pass near Earth [ Back to EurekAlert! ] Public release date: 31-May-2012
[ | E-mail | Share Share ]

Contact: Whitney Heins
wheins@utk.edu
865-974-5460
University of Tennessee at Knoxville

The work of a University of Tennessee, Knoxville, professor has helped reveal a rare orbital shift and the density of an asteroid that will pass close to Earth

The work of a University of Tennessee, Knoxville, professor has helped reveal a rare orbital shift and the density of an asteroid that will pass close to Earth.

Josh Emery, assistant professor of earth and planetary sciences, and the team of the NASA asteroid sample return mission called OSIRIS-REx have measured the weight and orbit of 1999 RQ36. They have found the asteroid has a low density and its orbit has drifted roughly 100 miles in the last 12 years. This deviation is caused by the Yarkovsky effect.

These findings were presented May 19 at the Asteroids, Comets and Meteors 2012 meeting in Niigata, Japan.

"This Yarkovsky effect can actually push an asteroid intoor out ofthe path of the Earth," said Emery. "Understanding this force and how it affects an asteroid is critical for determining whether or not that asteroid will hit us."

Emery's work using NASA's Spitzer Space Telescope in 2007 was crucial in determining the effect. He measured the asteroid's thermal characteristics using infrared emissions and determined the space rock was covered in an insulating blanket of fine materiala key factor for the effect.

"The longer a surface can hold heat, the stronger the Yarkovsky effect," said Emery. "Therefore, if the asteroid was made up of solid rock, the force would be stronger because it would retain heat longer. But fine material such as dust or sand heat up and cool down quickly so the effect is weaker."

The Yarkovsky effect sharpens the picture of how potentially hazardous 1999 RQ36 could be in the future. The 1,640-foot diameter asteroid is expected to pass by Earth in 2135 at around 220,000 miles. At such close distances, the asteroid's subsequent trajectory becomes impossible to accurately predict so close approaches can only be studied statistically.

Due to this discovery, scientists now have identified many low-probability potential impacts in the 2170s through the 2190s while ruling out others.

The Yarkovsky effect is named for the 19th-century Russian engineer who first proposed the idea that a small rocky space object would, over long periods of time, be noticeably nudged in its orbit when it absorbs sunlight and then re-emits that energy as heat. The effect is difficult to measure because it's so infinitesimally small.

The effect was discovered on 1999 RQ36 in an effort to determine the mass of the asteroid from millions of miles away. The scientists needed the space rock's size, thermal properties, propulsive force (Yarkovsky effect) and orbit to calculate the bulk density.

"Being able to find the weight of a solitary space object by using things like radar tracking and infrared observations might once have seemed almost science fiction," said Emery. "But now we have the tools to do it and we just use our findings and solve for 'x' which is the density."

The scientists discovered 1999 RQ36 has the density of water and is very porous.

"In addition to the excitement of the Yarkovsky results, we are excited to find that our asteroid consists mostly of dusts and rocks," said Emery. "Therefore, we should be able to get a collect a good sample to bring back to Earth and study."

The OSIRIS-REx spacecraft is scheduled to launch in 2016, arrive at the asteroid in 2019 and bring samples back to Earth in 2023.

The Origins, Spectral Interpretation, Resource Identification, Security, Regolith Explorer (OSIRIS-REs) mission is led by Professor Michael Drake of the University of Arizona.

The team includes researchers from the University of Arizona, NASA Goddard Space Flight Center, Lockheed Martin, Arizona State University, KinetX, the Canadian Space Agency, NASA Johnson Space Center, NASA Ames Research Center, and NASA Langley Research Center, along with science team members from across academia.

###

For more information about the discovery, visit http://uanews.org/node/47370 and http://www.jpl.nasa.gov/news/news.cfm?release=2012-145. For more information about the mission, visit http://osiris-rex.lpl.arizona.edu/.


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


University of Tennessee professor uncovers clues about asteroid that will pass near Earth [ Back to EurekAlert! ] Public release date: 31-May-2012
[ | E-mail | Share Share ]

Contact: Whitney Heins
wheins@utk.edu
865-974-5460
University of Tennessee at Knoxville

The work of a University of Tennessee, Knoxville, professor has helped reveal a rare orbital shift and the density of an asteroid that will pass close to Earth

The work of a University of Tennessee, Knoxville, professor has helped reveal a rare orbital shift and the density of an asteroid that will pass close to Earth.

Josh Emery, assistant professor of earth and planetary sciences, and the team of the NASA asteroid sample return mission called OSIRIS-REx have measured the weight and orbit of 1999 RQ36. They have found the asteroid has a low density and its orbit has drifted roughly 100 miles in the last 12 years. This deviation is caused by the Yarkovsky effect.

These findings were presented May 19 at the Asteroids, Comets and Meteors 2012 meeting in Niigata, Japan.

"This Yarkovsky effect can actually push an asteroid intoor out ofthe path of the Earth," said Emery. "Understanding this force and how it affects an asteroid is critical for determining whether or not that asteroid will hit us."

Emery's work using NASA's Spitzer Space Telescope in 2007 was crucial in determining the effect. He measured the asteroid's thermal characteristics using infrared emissions and determined the space rock was covered in an insulating blanket of fine materiala key factor for the effect.

"The longer a surface can hold heat, the stronger the Yarkovsky effect," said Emery. "Therefore, if the asteroid was made up of solid rock, the force would be stronger because it would retain heat longer. But fine material such as dust or sand heat up and cool down quickly so the effect is weaker."

The Yarkovsky effect sharpens the picture of how potentially hazardous 1999 RQ36 could be in the future. The 1,640-foot diameter asteroid is expected to pass by Earth in 2135 at around 220,000 miles. At such close distances, the asteroid's subsequent trajectory becomes impossible to accurately predict so close approaches can only be studied statistically.

Due to this discovery, scientists now have identified many low-probability potential impacts in the 2170s through the 2190s while ruling out others.

The Yarkovsky effect is named for the 19th-century Russian engineer who first proposed the idea that a small rocky space object would, over long periods of time, be noticeably nudged in its orbit when it absorbs sunlight and then re-emits that energy as heat. The effect is difficult to measure because it's so infinitesimally small.

The effect was discovered on 1999 RQ36 in an effort to determine the mass of the asteroid from millions of miles away. The scientists needed the space rock's size, thermal properties, propulsive force (Yarkovsky effect) and orbit to calculate the bulk density.

"Being able to find the weight of a solitary space object by using things like radar tracking and infrared observations might once have seemed almost science fiction," said Emery. "But now we have the tools to do it and we just use our findings and solve for 'x' which is the density."

The scientists discovered 1999 RQ36 has the density of water and is very porous.

"In addition to the excitement of the Yarkovsky results, we are excited to find that our asteroid consists mostly of dusts and rocks," said Emery. "Therefore, we should be able to get a collect a good sample to bring back to Earth and study."

The OSIRIS-REx spacecraft is scheduled to launch in 2016, arrive at the asteroid in 2019 and bring samples back to Earth in 2023.

The Origins, Spectral Interpretation, Resource Identification, Security, Regolith Explorer (OSIRIS-REs) mission is led by Professor Michael Drake of the University of Arizona.

The team includes researchers from the University of Arizona, NASA Goddard Space Flight Center, Lockheed Martin, Arizona State University, KinetX, the Canadian Space Agency, NASA Johnson Space Center, NASA Ames Research Center, and NASA Langley Research Center, along with science team members from across academia.

###

For more information about the discovery, visit http://uanews.org/node/47370 and http://www.jpl.nasa.gov/news/news.cfm?release=2012-145. For more information about the mission, visit http://osiris-rex.lpl.arizona.edu/.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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The right combination: Overcoming drug resistance in cancer

The right combination: Overcoming drug resistance in cancer [ Back to EurekAlert! ] Public release date: 1-Jun-2012
[ | E-mail | Share Share ]

Contact: Sarah Jackson
press_releases@the-jci.org
Journal of Clinical Investigation

Overactive epidermal growth factor receptor (EGFR) signaling has been linked to the development of cancer. Several drug therapies have been developed to treat these EGFR-associated cancers; however, many patients have developed resistance to these drugs and are therefore no longer responsive to drug treatment. In a recent research article published in the Journal of Clinical Investigation, Goutham Narla and colleagues at Case Western Reserve University sought to better understand the molecular players in the EGFR signaling pathway in hopes of finding new drug targets for EGFR-associated cancers. Using cancerous human lung tissue and a mouse model of EGFR-associated lung cancer, The Narla team discovered that two tumor suppressor genes, KLF6 and FOXO1, function to disrupt overactive EGFR signaling. After treating the cancerous lung tissue and cancer-prone mice with an FDA-approved drug called trifluoperazine hydrochloride (TFP), which increases the activity of FOXO1, they restored the effectiveness of the anti-EGFR drug erlotinib and reduced tumor growth. Their work identified new drug targets for EGFR-associated cancers and suggests that combinatorial drug therapy regimens may improve treatment outcome.

###

TITLE:

Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response

AUTHOR CONTACT:

Goutham Narla

Case Western Reserve University and University Hospitals, Cleveland, OH, USA

Phone: 347-255-0885; E-mail: Goutham.Narla@mssm.edu

View this article at: http://www.jci.org/articles/view/62058?key=9eb9f31baf7df0c3365e


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


The right combination: Overcoming drug resistance in cancer [ Back to EurekAlert! ] Public release date: 1-Jun-2012
[ | E-mail | Share Share ]

Contact: Sarah Jackson
press_releases@the-jci.org
Journal of Clinical Investigation

Overactive epidermal growth factor receptor (EGFR) signaling has been linked to the development of cancer. Several drug therapies have been developed to treat these EGFR-associated cancers; however, many patients have developed resistance to these drugs and are therefore no longer responsive to drug treatment. In a recent research article published in the Journal of Clinical Investigation, Goutham Narla and colleagues at Case Western Reserve University sought to better understand the molecular players in the EGFR signaling pathway in hopes of finding new drug targets for EGFR-associated cancers. Using cancerous human lung tissue and a mouse model of EGFR-associated lung cancer, The Narla team discovered that two tumor suppressor genes, KLF6 and FOXO1, function to disrupt overactive EGFR signaling. After treating the cancerous lung tissue and cancer-prone mice with an FDA-approved drug called trifluoperazine hydrochloride (TFP), which increases the activity of FOXO1, they restored the effectiveness of the anti-EGFR drug erlotinib and reduced tumor growth. Their work identified new drug targets for EGFR-associated cancers and suggests that combinatorial drug therapy regimens may improve treatment outcome.

###

TITLE:

Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response

AUTHOR CONTACT:

Goutham Narla

Case Western Reserve University and University Hospitals, Cleveland, OH, USA

Phone: 347-255-0885; E-mail: Goutham.Narla@mssm.edu

View this article at: http://www.jci.org/articles/view/62058?key=9eb9f31baf7df0c3365e


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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